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Masteron is an injectable preparation containing the steroid drostanolone propionate. Drostanolone is a derivative of dihydrotestosterone, most specifically 2alpha-methyldihydrotestosterone. As a result, the structure of this steroid is that of a moderate anabolic/potent androgen which does not aromatize to estrogen. Water retention and gynecomastia therefore do not come into play with this drug. Masteron may in fact exhibit anti-estrogenic activity in the body, competing with other substrates for binding to aromatase. This would reduce the conversion rate of other steroids, Masteron acting in the same way as the oral steroid Proviron.

Bodybuilders have a strong like for non-aromatizing androgens, and find Masteron very useful in a cutting phase. It is generally used for a number of weeks prior to a competition, in an effort to bring out an improved look of density and hardness to the muscles. As long as body fat percentage is low enough, Masteron should work very well. Provided everything fits as if should, the user can achieve that "ripped" look so popular to professional bodybuilding. The androgenic effect can also be crucial during this period, a time when caloric intake is drastically lowered. The user is provided added "kick" or "drive" to push through the grueling training sessions leading up to the show. Recreational users might also be interested in Masteron. Although dihydrotestosterone is not highly active in muscle tissue, the 2 alkylation present on drostanolone considerably intensifies its anabolic effect. It can therefore be used somewhat effectively as bulking agent, providing a consistent gain of high quality muscle mass. It can also be successfully combined with other steroids for an enhanced effect. Mixing drostanolone with an injectable anabolic such as Deca-Durabolin or Equipoise can prove quite useful for example, the two providing notably enhanced muscle gain without excessive water retention. For greater mass gains, a stronger androgen such as Dianabol or an injectable testosterone would do the trick. The result here can be an extreme muscle gain, with a lower level of water retention & other estrogenic side effects than if these steroids were used alone (usually in higher doses). Masteron could of course be used during cutting phases of training as well. A cycle of this drug combined with Winstrol, Primobolan or Oxandrolone should provide great muscle retention and fat loss, during a period which can be very catabolic without steroids. It is an added benefit that none of these steroids aromatize, and therefore there is no additional worry of unwanted water and fat retention.

Since the propionate ester is used with this compound, injections need to be repeated at least every 3 or 4 days in order to maintain a consistent level of hormone in the blood. The weekly dosage is in the range of 300-500mg.

Since estrogen is not an issue, side effects are generally mild with this steroid. As discussed earlier, gynecomastia, water retention, and high blood pressureare not a problem. Masteron is also not liver toxic, so there is little concern stress will be placed on this organ, even during longer cycles. The only real side effects would be from the basic androgenic properties of dihydrotestosterone. These includes oily skin, acne, body/facial hair growth, aggression and accelerated hair loss. Since this compound is already a synthetic DHT, Proscar would have no impact on the level of androgenic effects. Men with a receding hairline or those with a predisposition for baldness may therefore wish to stay away from Masteron completely, as the potent androgenic effect of this steroid can easily accelerate this condition.